WinRho prophylaxis would be indicated after which event?

WinRho prophylaxis would be indicated after which event?

• A. Following the birth of an Rh-negative newborn
• B. Following a spontaneous or induced abortion
• C. Following all births, regardless of blood type and Rh factor
• D. Following an ABO-incompatible birth

Answer: (B)

WinRho prophylaxis is given to an Rh-negative mother to prevent the development of antibodies to the RhD antigen when fetal blood could enter the mother’s circulation. After a spontaneous or induced abortion, fetal red cells can mix with maternal blood, creating a risk of sensitization. Providing Rh immune globulin in this situation prevents the mother from forming anti-D antibodies. It’s not routinely given after all births regardless of Rh status, because it’s specifically targeted to Rh-negative mothers with an Rh-positive fetus. ABO incompatibility involves different antigens and isn’t prevented by RhIg.

WinRho prophylaxis is given to an Rh-negative mother to prevent the development of antibodies to the RhD antigen when fetal blood could enter the mother’s circulation. After a spontaneous or induced abortion, fetal red cells can mix with maternal blood, creating a risk of sensitization. Providing Rh immune globulin in this situation prevents the mother from forming anti-D antibodies.

It’s not routinely given after all births regardless of Rh status, because it’s specifically targeted to Rh-negative mothers with an Rh-positive fetus. ABO incompatibility involves different antigens and isn’t prevented by RhIg.